Double knockin mice show NF-κB trajectories in immune signaling and aging

In vitro studies suggest that mapping the spatiotemporal complexity of nuclear factor κB (NF-κB) signaling is essential to understanding its function. The lack of tools to directly monitor NF-κB proteins in vivo has hindered such efforts. Here, we introduce reporter mice with the endogenous RelA (p6...

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Detalles Bibliográficos
Autores principales: Rahman, Shah Md Toufiqur, Aqdas, Mohammad, Martin, Erik W., Ardori, Francesco Tomassoni, Songkiatisak, Preeyaporn, Oh, Kyu-Seon, Uderhardt, Stefan, Yun, Sangwon, Claybourne, Quia C., McDevitt, Ross A., Greco, Valentina, Germain, Ronald N., Tessarollo, Lino, Sung, Myong-Hee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9764224/
https://www.ncbi.nlm.nih.gov/pubmed/36417863
http://dx.doi.org/10.1016/j.celrep.2022.111682

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