Cargando…

Glycan Conformation in the Heavily Glycosylated Protein, CEACAM1

[Image: see text] Glycans attached to glycoproteins can contribute to stability, mediate interactions with other proteins, and initiate signal transduction. Glycan conformation, which is critical to these processes, is highly variable and often depicted as sampling a multitude of conformers. These c...

Descripción completa

Detalles Bibliográficos
Autores principales:	Rogals, Monique J., Eletsky, Alexander, Huang, Chin, Morris, Laura C., Moremen, Kelley W., Prestegard, James H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2022
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9764281/ https://www.ncbi.nlm.nih.gov/pubmed/36417668 http://dx.doi.org/10.1021/acschembio.2c00714

Ejemplares similares

Site-to-site cross-talk in OST-B glycosylation of hCEACAM1-IgV
por: Williams, Robert V., et al.
Publicado: (2022)

Targeting Glycans and Heavily Glycosylated Proteins for Tumor Imaging
por: Houvast, Ruben D., et al.
Publicado: (2020)

Cell-based glycan arrays for probing glycan–glycan binding protein interactions
por: Briard, Jennie Grace, et al.
Publicado: (2018)

Validated determination of NRG1 Ig-like domain structure by mass spectrometry coupled with computational modeling
por: Khaje, Niloofar Abolhasani, et al.
Publicado: (2022)

NMR analysis suggests the terminal domains of Robo1 remain extended but are rigidified in the presence of heparan sulfate
por: Williams, Robert V., et al.
Publicado: (2022)

The S-Layer Protein of the Anammox Bacterium Kuenenia stuttgartiensis Is Heavily O-Glycosylated
por: van Teeseling, Muriel C. F., et al.
Publicado: (2016)

NMR Analysis Demonstrates Immunoglobulin G N-glycans are Accessible and Dynamic
por: Barb, Adam W., et al.
Publicado: (2011)

A Clickable Bioorthogonal Sydnone‐Aglycone for the Facile Preparation of a Core 1 O‐Glycan‐Array
por: Chinoy, Zoeisha S., et al.
Publicado: (2022)

Dissecting the conformation of glycans and their interactions with proteins
por: Wang, Sheng-Hung, et al.
Publicado: (2020)

Novel heavily fucosylated glycans as a promising therapeutic target in colorectal cancer
por: Tsai, Kuei-Yen, et al.
Publicado: (2023)

Influence of Side Chain Conformation on the Activity of Glycosidase Inhibitors
por: Tseng, Po‐Sen, et al.
Publicado: (2023)

O-Glycoproteomic analysis of engineered heavily glycosylated fusion proteins using nanoHILIC-MS
por: Cavallero, Gustavo J., et al.
Publicado: (2022)

Conformational Heterogeneity of the HIV Envelope Glycan Shield
por: Yang, Mingjun, et al.
Publicado: (2017)

Expression patterns of CEACAM5 and CEACAM6 in primary and metastatic cancers
por: Blumenthal, Rosalyn D, et al.
Publicado: (2007)

Role of CEACAM1 and CEACAM20 in an In Vitro Model of Prostate Morphogenesis
por: Zhang, Hui, et al.
Publicado: (2013)

Roles of N-linked glycosylation and glycan-binding proteins in placentation: trophoblast infiltration, immunomodulation, angiogenesis, and pathophysiology
por: Huang, Zhengyuan, et al.
Publicado: (2023)

Glycosylator: a Python framework for the rapid modeling of glycans
por: Lemmin, Thomas, et al.
Publicado: (2019)

Vulnerabilities in coronavirus glycan shields despite extensive glycosylation
por: Watanabe, Yasunori, et al.
Publicado: (2020)

Regioselective Glycosylation Strategies for the Synthesis of Group Ia and Ib Streptococcus Related Glycans Enable Elucidating Unique Conformations of the Capsular Polysaccharides
por: Del Bino, Linda, et al.
Publicado: (2019)

Streamlining the Chemoenzymatic Synthesis of Complex N-Glycans by a Stop and Go Strategy
por: Liu, Lin, et al.
Publicado: (2018)

Interactions of pathogenic Escherichia coli with CEACAMs
por: Sheikh, Alaullah, et al.
Publicado: (2023)

Generation of a monoclonal antibody recognizing the CEACAM glycan structure and inhibiting adhesion using cancer tissue-originated spheroid as an antigen
por: Sato, Yumi, et al.
Publicado: (2016)

Genetic determinants of genus-level glycan diversity in a bacterial protein glycosylation system
por: Hadjineophytou, Chris, et al.
Publicado: (2019)

T cell-mediated elimination of cancer cells by blocking CEACAM6–CEACAM1 interaction
por: Pinkert, Jessica, et al.
Publicado: (2021)

N-Glycosylation and N-Glycan Processing in HBV Biology and Pathogenesis
por: Dobrica, Mihaela-Olivia, et al.
Publicado: (2020)

Thyrotropin N-glycosylation and Glycan Composition in Severe Primary Hypothyroidism
por: Wide, Leif, et al.
Publicado: (2021)

Glycosylation network mapping and site-specific glycan maturation in vivo
por: Losfeld, Marie-Estelle, et al.
Publicado: (2022)

Sequential Analysis of the N/O-Glycosylation of Heavily Glycosylated HIV-1 gp120 Using EThcD-sceHCD-MS/MS
por: Zhang, Yong, et al.
Publicado: (2021)

Generation of a monoclonal antibody recognizing the heavily glycosylated CD45 protein and its application on identifying circulating tumor cells
por: Zhang, Weikai, et al.
Publicado: (2018)

CEACAMs: their role in physiology and pathophysiology
por: Kuespert, Katharina, et al.
Publicado: (2006)

Corrigendum: Generation of a monoclonal antibody recognizing the CEACAM glycan structure and inhibiting adhesion using cancer tissue-originated spheroid as an antigen
por: Sato, Yumi, et al.
Publicado: (2016)

Restricted N-glycan Conformational Space in the PDB and Its Implication in Glycan Structure Modeling
por: Jo, Sunhwan, et al.
Publicado: (2013)

O-fucosylation stabilizes the TSR3 motif in thrombospondin-1 by interacting with nearby amino acids and protecting a disulfide bond
por: Berardinelli, Steven J., et al.
Publicado: (2022)

Soluble CEACAM8 Interacts with CEACAM1 Inhibiting TLR2-Triggered Immune Responses
por: Singer, Bernhard B., et al.
Publicado: (2014)

Glycan Profile Analysis of Engineered Trastuzumab with Rationally Added Glycosylation Sequons Presents Significantly Increased Glycan Complexity
por: Cruz, Esteban, et al.
Publicado: (2021)

B4GAT1 is the priming enzyme for the LARGE-dependent functional glycosylation of α-dystroglycan
por: Praissman, Jeremy L, et al.
Publicado: (2014)

A General Protein O-Glycosylation Gene Cluster Encodes the Species-Specific Glycan of the Oral Pathogen Tannerella forsythia: O-Glycan Biosynthesis and Immunological Implications
por: Tomek, Markus B., et al.
Publicado: (2018)

Deciphering Protein Glycosylation by Computational Integration of On-chip Profiling, Glycan-array Data, and Mass Spectrometry
por: Klamer, Zachary, et al.
Publicado: (2019)

Characterization of Conformational Ensembles of Protonated N-glycans in the Gas-Phase
por: Re, Suyong, et al.
Publicado: (2018)

The S-Layer Glycoprotein of the Crenarchaeote Sulfolobus acidocaldarius Is Glycosylated at Multiple Sites with Chitobiose-Linked N-Glycans
por: Peyfoon, Elham, et al.
Publicado: (2010)

Cannot write session to /tmp/vufind_sessions/sess_2dbo1le9i24tduvs0rd985smuu