Zika virus infection of mature neurons from immunocompetent mice generates a disease-associated microglia and a tauopathy-like phenotype in link with a delayed interferon beta response

BACKGROUND: Zika virus (ZIKV) infection at postnatal or adult age can lead to neurological disorders associated with cognitive defects. Yet, how mature neurons respond to ZIKV remains substantially unexplored. METHODS: The impact of ZIKV infection on mature neurons and microglia was analyzed at the...

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Detalles Bibliográficos
Autores principales: Manet, Caroline, Mansuroglu, Zeyni, Conquet, Laurine, Bortolin, Violaine, Comptdaer, Thomas, Segrt, Helena, Bourdon, Marie, Menidjel, Reyene, Stadler, Nicolas, Tian, Guanfang, Herit, Floriane, Niedergang, Florence, Souès, Sylvie, Buée, Luc, Galas, Marie-Christine, Montagutelli, Xavier, Bonnefoy, Eliette
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9764315/
https://www.ncbi.nlm.nih.gov/pubmed/36539803
http://dx.doi.org/10.1186/s12974-022-02668-8

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