Mechanism of Action of Flavin-Dependent Halogenases

[Image: see text] To rationally engineer the substrate scope and selectivity of flavin-dependent halogenases (FDHs), it is essential to first understand the reaction mechanism and substrate interactions in the active site. FDHs have long been known to achieve regioselectivity through an electrophili...

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Detalles Bibliográficos
Autores principales: Barker, Rhys D., Yu, Yuqi, De Maria, Leonardo, Johannissen, Linus O., Scrutton, Nigel S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9764358/
https://www.ncbi.nlm.nih.gov/pubmed/36570077
http://dx.doi.org/10.1021/acscatal.2c05231

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9764358/
https://www.ncbi.nlm.nih.gov/pubmed/36570077
http://dx.doi.org/10.1021/acscatal.2c05231

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