A BioBricks Metabolic Engineering Platform for the Biosynthesis of Anthracyclinones in Streptomyces coelicolor

[Image: see text] Actinomycetes produce a variety of clinically indispensable molecules, such as antineoplastic anthracyclines. However, the actinomycetes are hindered in their further development as genetically engineered hosts for the synthesis of new anthracycline analogues due to their slow grow...

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Detalles Bibliográficos
Autores principales: Wang, Rongbin, Nguyen, Jennifer, Hecht, Jacob, Schwartz, Nora, Brown, Katelyn V., Ponomareva, Larissa V., Niemczura, Magdalena, van Dissel, Dino, van Wezel, Gilles P., Thorson, Jon S., Metsä-Ketelä, Mikko, Shaaban, Khaled A., Nybo, S. Eric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9764417/
https://www.ncbi.nlm.nih.gov/pubmed/36378506
http://dx.doi.org/10.1021/acssynbio.2c00498

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9764417/
https://www.ncbi.nlm.nih.gov/pubmed/36378506
http://dx.doi.org/10.1021/acssynbio.2c00498

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