Ring finger protein 126 promotes breast cancer metastasis and serves as a potential target to improve the therapeutic sensitivity of ATR inhibitors

BACKGROUND/AIMS: This study explores the relationship between the E3 ubiquitin ligase Ring finger protein 126 (RNF126) and early breast cancer metastasis and tests the hypothesis that RNF126 determines the efficacy of inhibitors targeting Ataxia telangiectasia mutated and Rad3-related kinase (ATR)....

Descripción completa

Detalles Bibliográficos
Autores principales: Pan, You, Yang, Yuchao, Huang, Rong, Yang, Huawei, Huang, Qinghua, Ji, Yinan, Dai, Jingxing, Qiao, Kun, Tang, Wei, Xie, Longgui, Yin, Ming, Ouyang, Jun, Ning, Shipeng, Su, Danke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9764525/
https://www.ncbi.nlm.nih.gov/pubmed/36539893
http://dx.doi.org/10.1186/s13058-022-01586-0

Ejemplares similares

Ejemplares similares