FOXO3a-dependent PARKIN negatively regulates cardiac hypertrophy by restoring mitophagy

BACKGROUND: Sustained cardiac hypertrophy often develops maladaptive myocardial remodeling, and eventually progresses to heart failure and sudden death. Therefore, maladaptive hypertrophy is considered as a critical therapeutic target for many heart diseases. Mitophagy, a crucial mechanism in mitoch...

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Detalles Bibliográficos
Autores principales: Sun, Teng, Han, Yu, Li, Jia-Lei, Jiao, Xiang-Ying, Zuo, Lin, Wang, Jin, Wang, Hai-Xiong, Yang, Jun-Li, Cao, Ji-Min, Wang, Jian-Xun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9764573/
https://www.ncbi.nlm.nih.gov/pubmed/36539848
http://dx.doi.org/10.1186/s13578-022-00935-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9764573/
https://www.ncbi.nlm.nih.gov/pubmed/36539848
http://dx.doi.org/10.1186/s13578-022-00935-y

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