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FOXO3a-dependent PARKIN negatively regulates cardiac hypertrophy by restoring mitophagy

BACKGROUND: Sustained cardiac hypertrophy often develops maladaptive myocardial remodeling, and eventually progresses to heart failure and sudden death. Therefore, maladaptive hypertrophy is considered as a critical therapeutic target for many heart diseases. Mitophagy, a crucial mechanism in mitoch...

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Detalles Bibliográficos
Autores principales:	Sun, Teng, Han, Yu, Li, Jia-Lei, Jiao, Xiang-Ying, Zuo, Lin, Wang, Jin, Wang, Hai-Xiong, Yang, Jun-Li, Cao, Ji-Min, Wang, Jian-Xun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9764573/ https://www.ncbi.nlm.nih.gov/pubmed/36539848 http://dx.doi.org/10.1186/s13578-022-00935-y

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