Cargando…
The dynamic communities of oral microbiome in neonates
The oral microbiome, associated with both oral disease and systemic disease, is in dynamic status along the whole life, and many factors including maternal microbiomes could impact the oral microbiome. While fewer studies have been conducted to study the characteristics of the oral microbiome in neo...
Autores principales: | , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9764626/ https://www.ncbi.nlm.nih.gov/pubmed/36560953 http://dx.doi.org/10.3389/fmicb.2022.1052525 |
_version_ | 1784853312061833216 |
---|---|
author | Guo, Haiying Li, Jin Yao, Hantao Liu, Yina Ji, Yaoting Zhang, Jing Zhao, Yun Du, Minquan |
author_facet | Guo, Haiying Li, Jin Yao, Hantao Liu, Yina Ji, Yaoting Zhang, Jing Zhao, Yun Du, Minquan |
author_sort | Guo, Haiying |
collection | PubMed |
description | The oral microbiome, associated with both oral disease and systemic disease, is in dynamic status along the whole life, and many factors including maternal microbiomes could impact the oral microbiome. While fewer studies have been conducted to study the characteristics of the oral microbiome in neonates and the associated maternal factors. Hence, we collected the microbiome of 15 mother-infant pairs across multiple body sites from birth up to 4 days postpartum and used high-throughput sequencing to characterize the microbiomes in mothers and their neonates. The oral microbiome in the neonates changed obviously during the 4 days after birth. Many bacteria originating from the vagina, skin, and environment disappeared in oral cavity over time, such as Prevotella bivia and Prevotella jejuni. Meanwhile, Staphylococcus epidermidis RP62A phage SP-beta, predominate bacterium in maternal skin microbiome and Streptococcus unclassified, main bacterium in vaginal microbiome, obviously increased in neonatal oral microbiome as time went on. Interestingly, as time progressed, the composition of the oral microbiome in the neonates was more similar to that of the milk microbiome in their mothers. Moreover, we found that the changes in the predominant bacteria in the neonates were in line with those in the neonates exposed to the environment. Together, these data described the sharp dynamics of the oral microbiome in neonates and the importance of maternal efforts in the development of the neonatal microbiome. |
format | Online Article Text |
id | pubmed-9764626 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-97646262022-12-21 The dynamic communities of oral microbiome in neonates Guo, Haiying Li, Jin Yao, Hantao Liu, Yina Ji, Yaoting Zhang, Jing Zhao, Yun Du, Minquan Front Microbiol Microbiology The oral microbiome, associated with both oral disease and systemic disease, is in dynamic status along the whole life, and many factors including maternal microbiomes could impact the oral microbiome. While fewer studies have been conducted to study the characteristics of the oral microbiome in neonates and the associated maternal factors. Hence, we collected the microbiome of 15 mother-infant pairs across multiple body sites from birth up to 4 days postpartum and used high-throughput sequencing to characterize the microbiomes in mothers and their neonates. The oral microbiome in the neonates changed obviously during the 4 days after birth. Many bacteria originating from the vagina, skin, and environment disappeared in oral cavity over time, such as Prevotella bivia and Prevotella jejuni. Meanwhile, Staphylococcus epidermidis RP62A phage SP-beta, predominate bacterium in maternal skin microbiome and Streptococcus unclassified, main bacterium in vaginal microbiome, obviously increased in neonatal oral microbiome as time went on. Interestingly, as time progressed, the composition of the oral microbiome in the neonates was more similar to that of the milk microbiome in their mothers. Moreover, we found that the changes in the predominant bacteria in the neonates were in line with those in the neonates exposed to the environment. Together, these data described the sharp dynamics of the oral microbiome in neonates and the importance of maternal efforts in the development of the neonatal microbiome. Frontiers Media S.A. 2022-12-06 /pmc/articles/PMC9764626/ /pubmed/36560953 http://dx.doi.org/10.3389/fmicb.2022.1052525 Text en Copyright © 2022 Guo, Li, Yao, Liu, Ji, Zhang, Zhao and Du. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Microbiology Guo, Haiying Li, Jin Yao, Hantao Liu, Yina Ji, Yaoting Zhang, Jing Zhao, Yun Du, Minquan The dynamic communities of oral microbiome in neonates |
title | The dynamic communities of oral microbiome in neonates |
title_full | The dynamic communities of oral microbiome in neonates |
title_fullStr | The dynamic communities of oral microbiome in neonates |
title_full_unstemmed | The dynamic communities of oral microbiome in neonates |
title_short | The dynamic communities of oral microbiome in neonates |
title_sort | dynamic communities of oral microbiome in neonates |
topic | Microbiology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9764626/ https://www.ncbi.nlm.nih.gov/pubmed/36560953 http://dx.doi.org/10.3389/fmicb.2022.1052525 |
work_keys_str_mv | AT guohaiying thedynamiccommunitiesoforalmicrobiomeinneonates AT lijin thedynamiccommunitiesoforalmicrobiomeinneonates AT yaohantao thedynamiccommunitiesoforalmicrobiomeinneonates AT liuyina thedynamiccommunitiesoforalmicrobiomeinneonates AT jiyaoting thedynamiccommunitiesoforalmicrobiomeinneonates AT zhangjing thedynamiccommunitiesoforalmicrobiomeinneonates AT zhaoyun thedynamiccommunitiesoforalmicrobiomeinneonates AT duminquan thedynamiccommunitiesoforalmicrobiomeinneonates AT guohaiying dynamiccommunitiesoforalmicrobiomeinneonates AT lijin dynamiccommunitiesoforalmicrobiomeinneonates AT yaohantao dynamiccommunitiesoforalmicrobiomeinneonates AT liuyina dynamiccommunitiesoforalmicrobiomeinneonates AT jiyaoting dynamiccommunitiesoforalmicrobiomeinneonates AT zhangjing dynamiccommunitiesoforalmicrobiomeinneonates AT zhaoyun dynamiccommunitiesoforalmicrobiomeinneonates AT duminquan dynamiccommunitiesoforalmicrobiomeinneonates |