Single-cell transcriptomic analysis reveals differential cell subpopulations and distinct phenotype transition in normal and dissected ascending aorta

BACKGROUND: Acute thoracic aortic dissection (ATAD) is a fatal condition characterized by tear of intima, formation of false lumen and rupture of aorta. However, the subpopulations of normal and dissected aorta remain less studied. METHODS: Single-cell RNA sequencing was performed including 5 patien...

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Detalles Bibliográficos
Autores principales: He, Yu-bin, Jin, Hai-zhen, Zhao, Jin-long, Wang, Chong, Ma, Wen-rui, Xing, Jie, Zhang, Xiao-bin, Zhang, Yang-yang, Dai, Huang-dong, Zhao, Nai-shi, Zhang, Jian-feng, Zhang, Guan-xin, Zhang, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9764678/
https://www.ncbi.nlm.nih.gov/pubmed/36536281
http://dx.doi.org/10.1186/s10020-022-00584-4

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