Cargando…

SRSF10 stabilizes CDC25A by triggering exon 6 skipping to promote hepatocarcinogenesis

BACKGROUND: Alternative splicing (AS) events are extensively involved in the progression of diverse tumors, but how serine/arginine-rich splicing Factor 10 (SRSF10) behaves in hepatocellular carcinoma (HCC) has not been sufficiently studied. We aimed to determine SRSF10 associated AS mechanisms and...

Descripción completa

Detalles Bibliográficos
Autores principales:	Liu, Xiaoming, Zheng, Yongqiang, Xiao, Mengqing, Chen, Xingyu, Zhu, Yuxing, Xu, Canxia, Wang, Fen, Liu, Zexian, Cao, Ke
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9764681/ https://www.ncbi.nlm.nih.gov/pubmed/36539837 http://dx.doi.org/10.1186/s13046-022-02558-0

Ejemplares similares

Activation of Cryptic 3′ Splice-Sites by SRSF2 Contributes to Cassette Exon Skipping
por: Moon, Heegyum, et al.
Publicado: (2019)

ExonSkipDB: functional annotation of exon skipping event in human
por: Kim, Pora, et al.
Publicado: (2020)

Exon skipping for DMD
por: Aartsma-Rus, Annemieke, et al.
Publicado: (2012)

RANBP2 Activates O-GlcNAcylation through Inducing CEBPα-Dependent OGA Downregulation to Promote Hepatocellular Carcinoma Malignant Phenotypes
por: Liu, Xiaoming, et al.
Publicado: (2021)

Combinatorial Pattern of Histone Modifications in Exon Skipping Event
por: Chen, Wei, et al.
Publicado: (2019)

Natural Exon Skipping Sets the Stage for Exon Skipping as Therapy for Dystrophic Epidermolysis Bullosa
por: Bremer, Jeroen, et al.
Publicado: (2019)

Therapeutic exon skipping for dysferlinopathies?
por: Aartsma-Rus, Annemieke, et al.
Publicado: (2010)

Widespread exon skipping triggers degradation by nuclear RNA surveillance in fission yeast
por: Bitton, Danny A., et al.
Publicado: (2015)

CLK1/SRSF5 pathway induces aberrant exon skipping of METTL14 and Cyclin L2 and promotes growth and metastasis of pancreatic cancer
por: Chen, Shi, et al.
Publicado: (2021)

Exon-Skipping in Duchenne Muscular Dystrophy
por: Takeda, Shin’ichi, et al.
Publicado: (2021)

Targeted Exon Skipping to Correct Exon Duplications in the Dystrophin Gene
por: Greer, Kane L, et al.
Publicado: (2014)

SRSF9 Regulates Cassette Exon Splicing of Caspase-2 by Interacting with Its Downstream Exon
por: Ha, Jiyeon, et al.
Publicado: (2021)

Insecticide resistance mediated by an exon skipping event
por: Berger, Madeleine, et al.
Publicado: (2016)

Therapeutic Prospects of Exon Skipping for Epidermolysis Bullosa
por: Vermeer, Franciscus C., et al.
Publicado: (2021)

Oxidative Stress Triggers Body-Wide Skipping of Multiple Exons of the Spinal Muscular Atrophy Gene
por: Seo, Joonbae, et al.
Publicado: (2016)

SRSF2 directly inhibits intron splicing to suppresses cassette exon inclusion
por: Moon, Heegyum, et al.
Publicado: (2017)

Myelodysplasia-associated mutations in serine/arginine-rich splicing factor SRSF2 lead to alternative splicing of CDC25C
por: Skrdlant, Lindsey, et al.
Publicado: (2016)

Prediction of alternatively skipped exons and splicing enhancers from exon junction arrays
por: Kechris, Katerina, et al.
Publicado: (2008)

Classifying Included and Excluded Exons in Exon Skipping Event Using Histone Modifications
por: Chen, Wei, et al.
Publicado: (2018)

A Genotype-Phenotype Correlation Study of Exon Skip-Equivalent In-Frame Deletions and Exon Skip-Amenable Out-of-Frame Deletions across the DMD Gene to Simulate the Effects of Exon-Skipping Therapies: A Meta-Analysis
por: Anwar, Saeed, et al.
Publicado: (2021)

Variants Affecting Exon Skipping Contribute to Complex Traits
por: Lee, Younghee, et al.
Publicado: (2012)

Multiple exon skipping strategies to by-pass dystrophin mutations
por: Adkin, Carl F., et al.
Publicado: (2012)

Elusive sources of variability of dystrophin rescue by exon skipping
por: Vila, Maria Candida, et al.
Publicado: (2015)

Skipping Multiple Exons to Treat DMD—Promises and Challenges
por: Aslesh, Tejal, et al.
Publicado: (2018)

Exon-skipping antisense oligonucleotides for cystic fibrosis therapy
por: Kim, Young Jin, et al.
Publicado: (2022)

Inhibition of Melanosome Transport by Inducing Exon Skipping in Melanophilin
por: Kim, Jin Young, et al.
Publicado: (2023)

Targeted exon skipping of NF1 exon 17 as a therapeutic for neurofibromatosis type I
por: Leier, André, et al.
Publicado: (2022)

Single Exon Skipping Can Address a Multi-Exon Duplication in the Dystrophin Gene
por: Greer, Kane, et al.
Publicado: (2020)

CRISPR-induced exon skipping is dependent on premature termination codon mutations
por: Sui, Tingting, et al.
Publicado: (2018)

Inhibition of the expression of oncogene SRSF3 by blocking an exonic splicing suppressor with antisense oligonucleotides
por: Guo, Jihua, et al.
Publicado: (2018)

Exon skipping-rich transcriptomes of animals reflect the significance of exon-shuffling in metazoan proteome evolution
por: Patthy, Laszlo
Publicado: (2019)

A spliceosomal twin intron (stwintron) participates in both exon skipping and evolutionary exon loss
por: Kavalecz, Napsugár, et al.
Publicado: (2019)

Novel Exon-Skipping Therapeutic Approach for the DMD Gene Based on Asymptomatic Deletions of Exon 49
por: Abaji, Mario, et al.
Publicado: (2022)

A compatible exon-exon junction database for the identification of exon skipping events using tandem mass spectrum data
por: Mo, Fan, et al.
Publicado: (2008)

Antisense-induced exon skipping for duplications in Duchenne muscular dystrophy
por: Aartsma-Rus, Annemieke, et al.
Publicado: (2007)

Dual exon skipping in myostatin and dystrophin for Duchenne muscular dystrophy
por: Kemaladewi, Dwi U, et al.
Publicado: (2011)

Targeted Exon Skipping to Address “Leaky” Mutations in the Dystrophin Gene
por: Fletcher, Sue, et al.
Publicado: (2012)

Deleterious c-Cbl Exon Skipping Contributes to Human Glioma()()
por: Seong, Min Woo, et al.
Publicado: (2015)

Exon Skipping in a Dysf-Missense Mutant Mouse Model
por: Malcher, Jakub, et al.
Publicado: (2018)

Unexpected consequences: exon skipping caused by CRISPR-generated mutations
por: Sharpe, Joshua J., et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_d7nms5inlj9b7fsciagestfufn