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Post-vaccine epidemiology of serotype 3 pneumococci identifies transformation inhibition through prophage-driven alteration of a non-coding RNA

BACKGROUND: The respiratory pathogen Streptococcus pneumoniae (the pneumococcus) is a genetically diverse bacterium associated with over 101 immunologically distinct polysaccharide capsules (serotypes). Polysaccharide conjugate vaccines (PCVs) have successfully eliminated multiple targeted serotypes...

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Detalles Bibliográficos
Autores principales:	Kwun, Min Jung, Ion, Alexandru V., Cheng, Hsueh-Chien, D’Aeth, Joshua C., Dougan, Sam, Oggioni, Marco R., Goulding, David A., Bentley, Stephen D., Croucher, Nicholas J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9764711/ https://www.ncbi.nlm.nih.gov/pubmed/36539881 http://dx.doi.org/10.1186/s13073-022-01147-2

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