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Movement Disorder in Demyelinating Disease: Tracing the Charcot's Foot Print
Movement disorders may be one of the neurological manifestations of demyelinating disorders. They can manifest in Parkinsonism or a wide spectrum of hyperkinetic movement disorders including tremor, paroxysmal dyskinesia, dystonia, chorea, and ballism. Some of these disorders occur during an acute e...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer - Medknow
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9764914/ https://www.ncbi.nlm.nih.gov/pubmed/36561038 http://dx.doi.org/10.4103/aian.aian_64_22 |
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author | Singh, Rashmi Pandey, Sanjay |
author_facet | Singh, Rashmi Pandey, Sanjay |
author_sort | Singh, Rashmi |
collection | PubMed |
description | Movement disorders may be one of the neurological manifestations of demyelinating disorders. They can manifest in Parkinsonism or a wide spectrum of hyperkinetic movement disorders including tremor, paroxysmal dyskinesia, dystonia, chorea, and ballism. Some of these disorders occur during an acute episode of demyelination, whereas others can develop later or even may precede the onset of the demyelinating disorders. The pathophysiology of movement disorders in demyelination is complex and the current evidence indicates a wide involvement of different brain networks and spinal cord. Treatment is mainly symptomatic and oral pharmacological agents are the mainstay of the management. Botulinum toxin and neurosurgical interventions may be required in selected patients. |
format | Online Article Text |
id | pubmed-9764914 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Wolters Kluwer - Medknow |
record_format | MEDLINE/PubMed |
spelling | pubmed-97649142022-12-21 Movement Disorder in Demyelinating Disease: Tracing the Charcot's Foot Print Singh, Rashmi Pandey, Sanjay Ann Indian Acad Neurol AIAN Review Movement disorders may be one of the neurological manifestations of demyelinating disorders. They can manifest in Parkinsonism or a wide spectrum of hyperkinetic movement disorders including tremor, paroxysmal dyskinesia, dystonia, chorea, and ballism. Some of these disorders occur during an acute episode of demyelination, whereas others can develop later or even may precede the onset of the demyelinating disorders. The pathophysiology of movement disorders in demyelination is complex and the current evidence indicates a wide involvement of different brain networks and spinal cord. Treatment is mainly symptomatic and oral pharmacological agents are the mainstay of the management. Botulinum toxin and neurosurgical interventions may be required in selected patients. Wolters Kluwer - Medknow 2022 2022-06-08 /pmc/articles/PMC9764914/ /pubmed/36561038 http://dx.doi.org/10.4103/aian.aian_64_22 Text en Copyright: © 2022 Annals of Indian Academy of Neurology https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms. |
spellingShingle | AIAN Review Singh, Rashmi Pandey, Sanjay Movement Disorder in Demyelinating Disease: Tracing the Charcot's Foot Print |
title | Movement Disorder in Demyelinating Disease: Tracing the Charcot's Foot Print |
title_full | Movement Disorder in Demyelinating Disease: Tracing the Charcot's Foot Print |
title_fullStr | Movement Disorder in Demyelinating Disease: Tracing the Charcot's Foot Print |
title_full_unstemmed | Movement Disorder in Demyelinating Disease: Tracing the Charcot's Foot Print |
title_short | Movement Disorder in Demyelinating Disease: Tracing the Charcot's Foot Print |
title_sort | movement disorder in demyelinating disease: tracing the charcot's foot print |
topic | AIAN Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9764914/ https://www.ncbi.nlm.nih.gov/pubmed/36561038 http://dx.doi.org/10.4103/aian.aian_64_22 |
work_keys_str_mv | AT singhrashmi movementdisorderindemyelinatingdiseasetracingthecharcotsfootprint AT pandeysanjay movementdisorderindemyelinatingdiseasetracingthecharcotsfootprint |