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Macrophage Mitochondrial Biogenesis and Metabolic Reprogramming Induced by Leishmania donovani Require Lipophosphoglycan and Type I Interferon Signaling

Pathogen-specific rewiring of host cell metabolism creates the metabolically adapted microenvironment required for pathogen replication. Here, we investigated the mechanisms governing the modulation of macrophage mitochondrial properties by the vacuolar pathogen Leishmania. We report that induction...

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Detalles Bibliográficos
Autores principales:	Acevedo Ospina, Hamlet, Guay-Vincent, Marie-Michèle, Descoteaux, Albert
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9764995/ https://www.ncbi.nlm.nih.gov/pubmed/36222510 http://dx.doi.org/10.1128/mbio.02578-22

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