Pharmacokinetic-Pharmacodynamic Target Attainment Analyses as Support for Meropenem-Vaborbactam Dosing Regimens and Susceptibility Breakpoints

Meropenem-vaborbactam is a fixed-dose beta-lactam/beta-lactamase inhibitor with potent in vitro and in vivo activity against Klebsiella pneumoniae carbapenemase (KPC)-producing Enterobacterales. Pharmacokinetic-pharmacodynamic (PK-PD) target attainment analyses were undertaken using population pharm...

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Detalles Bibliográficos
Autores principales: Bhavnani, S. M., Trang, M., Griffith, D. C., Lomovskaya, O., Hammel, J. P., Loutit, J. S., Cammarata, S. K., Dudley, M. N., Ambrose, P. G., Rubino, C. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9764998/
https://www.ncbi.nlm.nih.gov/pubmed/36374023
http://dx.doi.org/10.1128/aac.02130-21

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9764998/
https://www.ncbi.nlm.nih.gov/pubmed/36374023
http://dx.doi.org/10.1128/aac.02130-21

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