Accessing the Variability of Multicopy Genes in Complex Genomes using Unassembled Next-Generation Sequencing Reads: The Case of Trypanosoma cruzi Multigene Families

Repetitive elements cause assembly fragmentation in complex eukaryotic genomes, limiting the study of their variability. The genome of Trypanosoma cruzi, the parasite that causes Chagas disease, has a high repetitive content, including multigene families. Although many T. cruzi multigene families en...

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Detalles Bibliográficos
Autores principales: Reis-Cunha, João Luís, Coqueiro-dos-Santos, Anderson, Pimenta-Carvalho, Samuel Alexandre, Marques, Larissa Pinheiro, Rodrigues-Luiz, Gabriela F., Baptista, Rodrigo P., de Almeida, Laila Viana, Honorato, Nathan Ravi Medeiros, Lobo, Francisco Pereira, Fraga, Vanessa Gomes, Galvão, Lucia Maria da Cunha, Bueno, Lilian Lacerda, Fujiwara, Ricardo Toshio, Cardoso, Mariana Santos, Cerqueira, Gustavo Coutinho, Bartholomeu, Daniella C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9765020/
https://www.ncbi.nlm.nih.gov/pubmed/36264102
http://dx.doi.org/10.1128/mbio.02319-22

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