The Trisubstituted Isoxazole MMV688766 Exerts Broad-Spectrum Activity against Drug-Resistant Fungal Pathogens through Inhibition of Lipid Homeostasis

Candida species are among the most prevalent causes of systemic fungal infection, posing a growing threat to public health. While Candida albicans is the most common etiological agent of systemic candidiasis, the frequency of infections caused by non-albicans Candida species is rising. Among these i...

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Detalles Bibliográficos
Autores principales: Puumala, Emily, Zaslaver, Olga, Chen, Amy, Duncan, Dustin, Fogal, Meea, Shapiro, Rebecca S., Mazhab-Jafari, Mohammad T., Whitesell, Luke, Montenegro-Burke, J. Rafael, Robbins, Nicole, Cowen, Leah E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9765174/
https://www.ncbi.nlm.nih.gov/pubmed/36300931
http://dx.doi.org/10.1128/mbio.02730-22

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