An Evolutionary Paradigm Favoring Cross Talk between Bacterial Two-Component Signaling Systems

The prevalent paradigm governing bacterial two-component signaling systems (TCSs) is specificity, wherein the histidine kinase (HK) of a TCS exclusively activates its cognate response regulator (RR). Cross talk, where HKs activate noncognate RRs, is considered evolutionarily disadvantageous because...

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Detalles Bibliográficos
Autores principales: Vemparala, Bharadwaj, Valiya Parambathu, Arjun, Saini, Deepak Kumar, Dixit, Narendra M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9765234/
https://www.ncbi.nlm.nih.gov/pubmed/36264076
http://dx.doi.org/10.1128/msystems.00298-22

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