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Dickkopf1 fuels inflammatory cytokine responses
Many human diseases, including cancer, share an inflammatory component but the molecular underpinnings remain incompletely understood. We report that physiological and pathological Dickkopf1 (DKK1) activity fuels inflammatory cytokine responses in cell models, mice and humans. DKK1 maintains the ele...
Autores principales: | Jaschke, Nikolai P., Pählig, Sophie, Sinha, Anupam, Adolph, Timon E., Colunga, Maria Ledesma, Hofmann, Maura, Wang, Andrew, Thiele, Sylvia, Schwärzler, Julian, Kleymann, Alexander, Gentzel, Marc, Tilg, Herbert, Wielockx, Ben, Hofbauer, Lorenz C., Rauner, Martina, Göbel, Andy, Rachner, Tilman D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9765382/ https://www.ncbi.nlm.nih.gov/pubmed/36539532 http://dx.doi.org/10.1038/s42003-022-04368-8 |
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