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Dickkopf1 fuels inflammatory cytokine responses

Many human diseases, including cancer, share an inflammatory component but the molecular underpinnings remain incompletely understood. We report that physiological and pathological Dickkopf1 (DKK1) activity fuels inflammatory cytokine responses in cell models, mice and humans. DKK1 maintains the ele...

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Detalles Bibliográficos
Autores principales: Jaschke, Nikolai P., Pählig, Sophie, Sinha, Anupam, Adolph, Timon E., Colunga, Maria Ledesma, Hofmann, Maura, Wang, Andrew, Thiele, Sylvia, Schwärzler, Julian, Kleymann, Alexander, Gentzel, Marc, Tilg, Herbert, Wielockx, Ben, Hofbauer, Lorenz C., Rauner, Martina, Göbel, Andy, Rachner, Tilman D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9765382/
https://www.ncbi.nlm.nih.gov/pubmed/36539532
http://dx.doi.org/10.1038/s42003-022-04368-8

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