The ESX-1 Substrate PPE68 Has a Key Function in ESX-1-Mediated Secretion in Mycobacterium marinum

Mycobacteria use specialized type VII secretion systems (T7SSs) to secrete proteins across their diderm cell envelope. One of the T7SS subtypes, named ESX-1, is a major virulence determinant in pathogenic species such as Mycobacterium tuberculosis and the fish pathogen Mycobacterium marinum. ESX-1 s...

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Detalles Bibliográficos
Autores principales: Damen, Merel P. M., Meijers, Aniek S., Keizer, Esther M., Piersma, Sander R., Jiménez, Connie R., Kuijl, Coenraad P., Bitter, Wilbert, Houben, Edith N. G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9765416/
https://www.ncbi.nlm.nih.gov/pubmed/36409073
http://dx.doi.org/10.1128/mbio.02819-22

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