Structures of Fission Yeast Inositol Pyrophosphate Kinase Asp1 in Ligand-Free, Substrate-Bound, and Product-Bound States

Expression of the fission yeast Schizosaccharomyces pombe phosphate regulon is sensitive to the intracellular level of the inositol pyrophosphate signaling molecule 1,5-IP(8). IP(8) dynamics are determined by Asp1, a bifunctional enzyme consisting of an N-terminal kinase domain and a C-terminal pyro...

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Detalles Bibliográficos
Autores principales: Benjamin, Bradley, Goldgur, Yehuda, Jork, Nikolaus, Jessen, Henning J., Schwer, Beate, Shuman, Stewart
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9765450/
https://www.ncbi.nlm.nih.gov/pubmed/36468882
http://dx.doi.org/10.1128/mbio.03087-22

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9765450/
https://www.ncbi.nlm.nih.gov/pubmed/36468882
http://dx.doi.org/10.1128/mbio.03087-22

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