Use of the Human Granulysin Transgenic Mice To Evaluate the Role of Granulysin Expression by CD8 T Cells in Immunity To Mycobacterium tuberculosis

The cytotoxic granules of human NK and CD8 T cells contain the effector molecule granulysin. Although in vitro studies indicate that granulysin is bactericidal to Mycobacterium tuberculosis and human CD8 T cells restrict intracellular M. tuberculosis by granule exocytosis, the role of granulysin in...

Descripción completa

Detalles Bibliográficos
Autores principales: Thakur, Preeti, Sutiwisesak, Rujapak, Lu, Yu-Jung, Behar, Samuel M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9765553/
https://www.ncbi.nlm.nih.gov/pubmed/36409085
http://dx.doi.org/10.1128/mbio.03020-22

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9765553/
https://www.ncbi.nlm.nih.gov/pubmed/36409085
http://dx.doi.org/10.1128/mbio.03020-22

Ejemplares similares