Extension of O-Linked Mannosylation in the Golgi Apparatus Is Critical for Cell Wall Integrity Signaling and Interaction with Host Cells in Cryptococcus neoformans Pathogenesis

The human-pathogenic yeast Cryptococcus neoformans assembles two types of O-linked glycans on its proteins. In this study, we identified and functionally characterized the C. neoformans CAP6 gene, encoding an α1,3-mannosyltransferase responsible for the second mannose addition to minor O-glycans con...

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Detalles Bibliográficos
Autores principales: Thak, Eun Jung, Son, Ye Ji, Lee, Dong-Jik, Kim, Hyunah, Kim, Jung Ho, Lee, Su-Bin, Jang, Yu-Byeong, Bahn, Yong-Sun, Nichols, Connie B., Alspaugh, J. Andrew, Kang, Hyun Ah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9765558/
https://www.ncbi.nlm.nih.gov/pubmed/36409123
http://dx.doi.org/10.1128/mbio.02112-22

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