IMPACT OF COMBINATIONS OF THE APOE Ɛ4 ALLELE AND TOMM40-APOC1 VARIANTS ON SURVIVAL TO OLDER AGES AND ALZHEIMER’S RISK

Multifactorial diseases, health-related traits, and lifespan are polygenic phenotypes with complex genetic architectures. Polygenicity implies that multiple variants can impact the risks of these phenotypes independently or jointly. Recently, we showed that carriers of minor alleles of rs429358 (APO...

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Detalles Bibliográficos
Autores principales: Kulminski, Alexander, Jain-Washburn, Ethan, Philipp, Ian, Arbeev, Konstantin, Stallard, Eric, Feitosa, Mary, Schupf, Nicole, Christensen, Kaare
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Abstracts
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9765755/
http://dx.doi.org/10.1093/geroni/igac059.1732

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9765755/
http://dx.doi.org/10.1093/geroni/igac059.1732

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