CELL SENESCENCE IS A FEATURE AND MODULATOR OF THE AGED INFLAMMATORY BRAIN CELL LANDSCAPE

New strategies to preserve cognitive function could broadly benefit the aging population. Cellular senescence is a hypothesized mediator of inflammation-related tissue dysfunction in aging. Using single-cell RNA-sequencing, we discovered an age-related brain myeloid population exhibiting overlapping...

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Detalles Bibliográficos
Autores principales: Schafer, Marissa, Zhang, Xu, Carver, Chase, Pearsall, Vesselina, Atkinson, Elizabeth, Clarkson, Benjamin, Grund, Ethan, LeBrasseur, Nathan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Abstracts
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9765795/
http://dx.doi.org/10.1093/geroni/igac059.781

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