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CORRELATES OF ELEVATED C-REACTIVE PROTEIN AMONG BLACK OLDER ADULTS: EVIDENCE FROM THE HEALTH AND RETIREMENT STUDY

Substantial evidence documents gender and racial disparities in C-reactive protein (CRP), a measure of systemic inflammation, among older adults. Yet, the comparative approaches of these studies may obscure distinct risk and protective factors associated with elevated CRP among older Black Americans...

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Autores principales: Farmer, Heather, Tobin, Courtney Sinclair, Thorpe, Jr., Roland J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9766078/
http://dx.doi.org/10.1093/geroni/igac059.879
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author Farmer, Heather
Tobin, Courtney Sinclair
Thorpe, Jr., Roland J
author_facet Farmer, Heather
Tobin, Courtney Sinclair
Thorpe, Jr., Roland J
author_sort Farmer, Heather
collection PubMed
description Substantial evidence documents gender and racial disparities in C-reactive protein (CRP), a measure of systemic inflammation, among older adults. Yet, the comparative approaches of these studies may obscure distinct risk and protective factors associated with elevated CRP among older Black Americans. To pinpoint opportunities for intervention, this study utilizes a “within-group approach” to identify the sociodemographic, psychosocial, behavioral, and health-related determinants of elevated CRP among older Black women and men. The sample consisted of 2,420 Black respondents aged 51+ in the Health and Retirement Study (2006-2016). Gender-stratified, random effects logistic regression models were used to examine determinants of elevated CRP (>3.0 mg/L). More than 50% of Black women had elevated CRP, and we found that younger age, Medicaid, lower mastery, religiosity, overweight/obesity, physical inactivity, and ADLs contributed to elevated CRP among this group. In contrast, elevated CRP was reported among only 37.25% of Black men, for whom financial distress was associated with lower odds of elevated CRP; religiosity, less neighborhood cohesion, current smoking, overweight/obesity, ADLs, and more chronic conditions were associated with greater odds of elevated CRP among this group. Sociodemographic factors had a limited association with elevated CRP among older Black Americans. Rather, a range of psychosocial, behavioral, and health-related factors were more influential determinants of elevated CRP among older Black Americans. Most notably, findings demonstrate distinct determinants of CRP among Black women and men, underscoring the critical need to further evaluate the risk and protective mechanisms undergirding disparities among this aging population.
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spelling pubmed-97660782022-12-20 CORRELATES OF ELEVATED C-REACTIVE PROTEIN AMONG BLACK OLDER ADULTS: EVIDENCE FROM THE HEALTH AND RETIREMENT STUDY Farmer, Heather Tobin, Courtney Sinclair Thorpe, Jr., Roland J Innov Aging Abstracts Substantial evidence documents gender and racial disparities in C-reactive protein (CRP), a measure of systemic inflammation, among older adults. Yet, the comparative approaches of these studies may obscure distinct risk and protective factors associated with elevated CRP among older Black Americans. To pinpoint opportunities for intervention, this study utilizes a “within-group approach” to identify the sociodemographic, psychosocial, behavioral, and health-related determinants of elevated CRP among older Black women and men. The sample consisted of 2,420 Black respondents aged 51+ in the Health and Retirement Study (2006-2016). Gender-stratified, random effects logistic regression models were used to examine determinants of elevated CRP (>3.0 mg/L). More than 50% of Black women had elevated CRP, and we found that younger age, Medicaid, lower mastery, religiosity, overweight/obesity, physical inactivity, and ADLs contributed to elevated CRP among this group. In contrast, elevated CRP was reported among only 37.25% of Black men, for whom financial distress was associated with lower odds of elevated CRP; religiosity, less neighborhood cohesion, current smoking, overweight/obesity, ADLs, and more chronic conditions were associated with greater odds of elevated CRP among this group. Sociodemographic factors had a limited association with elevated CRP among older Black Americans. Rather, a range of psychosocial, behavioral, and health-related factors were more influential determinants of elevated CRP among older Black Americans. Most notably, findings demonstrate distinct determinants of CRP among Black women and men, underscoring the critical need to further evaluate the risk and protective mechanisms undergirding disparities among this aging population. Oxford University Press 2022-12-20 /pmc/articles/PMC9766078/ http://dx.doi.org/10.1093/geroni/igac059.879 Text en © The Author(s) 2022. Published by Oxford University Press on behalf of The Gerontological Society of America. https://creativecommons.org/licenses/by/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Abstracts
Farmer, Heather
Tobin, Courtney Sinclair
Thorpe, Jr., Roland J
CORRELATES OF ELEVATED C-REACTIVE PROTEIN AMONG BLACK OLDER ADULTS: EVIDENCE FROM THE HEALTH AND RETIREMENT STUDY
title CORRELATES OF ELEVATED C-REACTIVE PROTEIN AMONG BLACK OLDER ADULTS: EVIDENCE FROM THE HEALTH AND RETIREMENT STUDY
title_full CORRELATES OF ELEVATED C-REACTIVE PROTEIN AMONG BLACK OLDER ADULTS: EVIDENCE FROM THE HEALTH AND RETIREMENT STUDY
title_fullStr CORRELATES OF ELEVATED C-REACTIVE PROTEIN AMONG BLACK OLDER ADULTS: EVIDENCE FROM THE HEALTH AND RETIREMENT STUDY
title_full_unstemmed CORRELATES OF ELEVATED C-REACTIVE PROTEIN AMONG BLACK OLDER ADULTS: EVIDENCE FROM THE HEALTH AND RETIREMENT STUDY
title_short CORRELATES OF ELEVATED C-REACTIVE PROTEIN AMONG BLACK OLDER ADULTS: EVIDENCE FROM THE HEALTH AND RETIREMENT STUDY
title_sort correlates of elevated c-reactive protein among black older adults: evidence from the health and retirement study
topic Abstracts
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9766078/
http://dx.doi.org/10.1093/geroni/igac059.879
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