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SPERMIDINE TOXICITY IN MITOCHONDRIAL DNA-DEFICIENT SACCHAROMYCES CEREVISIAE
Mitochondrial dysfunction is thought to play a significant role in aging and in manyhuman diseases. Over the last 20 years or so, a number of drugs have been found toextend lifespan in model organisms. Using ethidium bromide to deplete the yeastSaccharomyces cerevisiae of its mitochondrial DNA (mtDN...
Autores principales: | Su, Wei-Hsuan, Ocegueda, Omar, Choi, Catherine, Smith, Jessica, Lee, Kelsey, Wan, Yihan, Yao, Jacqueline, Schriner, Sam |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9766332/ http://dx.doi.org/10.1093/geroni/igac059.1740 |
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