CYP2C19 genotype and platelet aggregation test-guided dual antiplatelet therapy after off-pump coronary artery bypass grafting: A retrospective cohort study

BACKGROUND: Dual antiplatelet therapy (DAPT) is recommended in patients undergoing off-pump coronary artery bypass graft surgery (OPCAB). Clopidogrel is less effective among patients with loss-of-function (LoF) of CYP2C19 alleles, while ticagrelor has direct effects on P2Y(12) receptor. Whether a CY...

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Detalles Bibliográficos
Autores principales: Yao, Haoyi, Qin, Kaijie, Liu, Yun, Yang, Yi, Zhu, Jiaxi, Chen, Anqing, Wang, Zhe, Ye, Xiaofeng, Zhou, Mi, Li, Haiqing, Qiu, Jiapei, Zhao, Qiang, Zhu, Yunpeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Cardiovascular Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9766355/
https://www.ncbi.nlm.nih.gov/pubmed/36561777
http://dx.doi.org/10.3389/fcvm.2022.1023004

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