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SASP PROTEIN ASSOCIATIONS WITH HUMAN AGING HIGHLIGHTS THE ROLE OF GDF15, CST3, AND IGFBP2

Cellular senescence is a hallmark of aging and can result in a Senescence-Associated Secretory Phenotype (SASP). SASP is characterized by an increased production of proinflammatory cytokines and damage to surrounding tissues. There is substantial evidence from non-human models demonstrating that SAS...

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Detalles Bibliográficos
Autores principales: Evans, Daniel, Young, Danielle, Tanaka, Toshiko, Basisty, Nathan, Ferrucci, Luigi, Campisi, Judith, Schilling, Birgit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9767004/
http://dx.doi.org/10.1093/geroni/igac059.2929