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Design and Optimization of Rivaroxaban-Cyclodextrin-Polymer Triple Complex Formulation with Improved Solubility

PURPOSE: This study aimed to ensure the convenience of administration and reproducibility of efficacy, regardless of the meal, by improving the solubility of rivaroxaban (RIV). METHODS: RIV is a non-vitamin K antagonist oral anticoagulants that exhibits a coagulation effect by directly inhibiting co...

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Detalles Bibliográficos
Autores principales:	Kang, Ji-Hyun, Lee, Ji-Eun, Jeong, So-Jeong, Park, Chun-Woong, Kim, Dong-Wook, Weon, Kwon-Yeon
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2022
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9767707/ https://www.ncbi.nlm.nih.gov/pubmed/36561308 http://dx.doi.org/10.2147/DDDT.S389884

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