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An in-silico pharmacophore-based molecular docking study to evaluate the inhibitory potentials of novel fungal triterpenoid Astrakurkurone analogues against a hypothetical mutated main protease of SARS-CoV-2 virus

BACKGROUND: The main protease is an important structural protein of SARS-CoV-2, essential for its survivability inside a human host. Considering current vaccines' limitations and the absence of approved therapeutic targets, M(pro) may be regarded as the potential candidate drug target. Novel fu...

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Detalles Bibliográficos
Autores principales:	Nag, Anish, Dasgupta, Adhiraj, Sengupta, Sutirtha, Lai, Tapan Kumar, Acharya, Krishnendu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier Ltd. 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9767885/ https://www.ncbi.nlm.nih.gov/pubmed/36565483 http://dx.doi.org/10.1016/j.compbiomed.2022.106433

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