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Emergence of heartbeat frailty in advanced age I: perspectives from life-long EKG recordings in adult mice
The combined influences of sinoatrial nodal (SAN) pacemaker cell automaticity and its response to autonomic input determine the heart’s beating interval variability and mean beating rate. To determine the intrinsic SAN and autonomic signatures buried within EKG RR interval time series change in adva...
Autores principales: | Moen, Jack M., Morrell, Christopher H., Matt, Michael G., Ahmet, Ismayil, Tagirova, Syevda, Davoodi, Moran, Petr, Michael, Charles, Shaquille, de Cabo, Rafael, Yaniv, Yael, Lakatta, Edward G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9768068/ https://www.ncbi.nlm.nih.gov/pubmed/35759167 http://dx.doi.org/10.1007/s11357-022-00605-4 |
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