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Effects of coiling embolism on blood hemodynamic of the MCA aneurysm: a numerical study

One of common endovascular technique for treatment of MCA aneurysm is using coiling gel for limiting of blood stream. In this work, computational fluid dynamic is used for the simulation of the blood hemodynamic inside MCA in existence of coiling gel. This work has tried to visualize the impacts of...

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Autor principal: Valipour, Peiman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9768123/
https://www.ncbi.nlm.nih.gov/pubmed/36539436
http://dx.doi.org/10.1038/s41598-022-26208-9
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author Valipour, Peiman
author_facet Valipour, Peiman
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description One of common endovascular technique for treatment of MCA aneurysm is using coiling gel for limiting of blood stream. In this work, computational fluid dynamic is used for the simulation of the blood hemodynamic inside MCA in existence of coiling gel. This work has tried to visualize the impacts of blood characteristics i.e. hematocrit as a protein related factor on efficiency of coiling fiber inside the aneurysm. Tufts of polyester fibers may be attached to the coil to support thrombosis and platelet aggregation. Blood rheology analysis is done by solving RANS equations and it is assumed that blood stream is non-Newtonian with fluid–solid interaction. OSI and WSS are compared on sac surface area for different stages of blood cycle. Achieved results confirm that the coiling gel substantially decreases the blood circulation inside the aneurysm sac. It is also found that the influence of blood hematocrit decreases when the MCA aneurysm is filled by the coiling gel.
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spelling pubmed-97681232022-12-22 Effects of coiling embolism on blood hemodynamic of the MCA aneurysm: a numerical study Valipour, Peiman Sci Rep Article One of common endovascular technique for treatment of MCA aneurysm is using coiling gel for limiting of blood stream. In this work, computational fluid dynamic is used for the simulation of the blood hemodynamic inside MCA in existence of coiling gel. This work has tried to visualize the impacts of blood characteristics i.e. hematocrit as a protein related factor on efficiency of coiling fiber inside the aneurysm. Tufts of polyester fibers may be attached to the coil to support thrombosis and platelet aggregation. Blood rheology analysis is done by solving RANS equations and it is assumed that blood stream is non-Newtonian with fluid–solid interaction. OSI and WSS are compared on sac surface area for different stages of blood cycle. Achieved results confirm that the coiling gel substantially decreases the blood circulation inside the aneurysm sac. It is also found that the influence of blood hematocrit decreases when the MCA aneurysm is filled by the coiling gel. Nature Publishing Group UK 2022-12-20 /pmc/articles/PMC9768123/ /pubmed/36539436 http://dx.doi.org/10.1038/s41598-022-26208-9 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Article
Valipour, Peiman
Effects of coiling embolism on blood hemodynamic of the MCA aneurysm: a numerical study
title Effects of coiling embolism on blood hemodynamic of the MCA aneurysm: a numerical study
title_full Effects of coiling embolism on blood hemodynamic of the MCA aneurysm: a numerical study
title_fullStr Effects of coiling embolism on blood hemodynamic of the MCA aneurysm: a numerical study
title_full_unstemmed Effects of coiling embolism on blood hemodynamic of the MCA aneurysm: a numerical study
title_short Effects of coiling embolism on blood hemodynamic of the MCA aneurysm: a numerical study
title_sort effects of coiling embolism on blood hemodynamic of the mca aneurysm: a numerical study
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9768123/
https://www.ncbi.nlm.nih.gov/pubmed/36539436
http://dx.doi.org/10.1038/s41598-022-26208-9
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