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The novel anti-cancer feature of Brazzein through activating of hTLR5 by integration of biological evaluation: molecular docking and molecular dynamics simulation

Many of plant proteins exhibit the properties similar to the antitumor proteins although the anticancer activity of Brazzein on modulating the autophagy signaling pathway has not been determined so far. The present study aimed to develop a simplified system to enable the rational design of the activ...

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Detalles Bibliográficos
Autores principales: Poursalim, Maede, Shasaltaneh, Marzieh Dehghan, Jafarian, Vahab, Salehabadi, Hafezeh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9768156/
https://www.ncbi.nlm.nih.gov/pubmed/36539522
http://dx.doi.org/10.1038/s41598-022-26487-2