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Novel insights into mouse models of ectopic proplatelet release

Mature bone marrow (BM) megakaryocytes (MKs) produce platelets by extending proplatelets into sinusoidal blood vessels. Defects in this process can lead to thrombocytopenia and increased risk of bleeding. Mice lacking the actin-regulatory proteins Profilin 1 (PFN1), Wiskott–Aldrich Syndrome protein...

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Detalles Bibliográficos
Autores principales:	Spindler, Markus, Bergmeier, Wolfgang, Stradal, Theresia E. B., Zhang, Jinyi, Siminovitch, Katherine A., Nicolai, Leo, Reinhold, Annegret, Bender, Markus
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The American Society of Hematology 2022
Materias:	Stimulus Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9768245/ https://www.ncbi.nlm.nih.gov/pubmed/36251748 http://dx.doi.org/10.1182/bloodadvances.2022007824

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