Cargando…
Cooperation between cGAS and RIG-I sensing pathways enables improved innate recognition of HIV-1 by myeloid dendritic cells in elite controllers
INTRODUCTION: Spontaneous control of HIV-1 replication in the absence of anti-retroviral therapy (ART) naturally occurs in a small proportion of HIV-1-infected individuals known as elite controllers (EC), likely as a result of improved innate and adaptive immune mechanisms. Previous studies suggest...
Autores principales: | Martin-Gayo, Enrique, Gao, Ce, Calvet-Mirabent, Marta, Ouyang, Zhengyu, Lichterfeld, Mathias, Yu, Xu G. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9768436/ https://www.ncbi.nlm.nih.gov/pubmed/36569826 http://dx.doi.org/10.3389/fimmu.2022.1017164 |
Ejemplares similares
-
Potent Cell-Intrinsic Immune Responses in Dendritic Cells Facilitate HIV-1-Specific T Cell Immunity in HIV-1 Elite Controllers
por: Martin-Gayo, Enrique, et al.
Publicado: (2015) -
Effective innate immune response in natural HIV-1 controllers. Can mimicking lead to novel preventive and cure strategies against HIV-1?
por: Calvet-Mirabent, Marta, et al.
Publicado: (2022) -
A Reproducibility-Based Computational Framework Identifies an Inducible, Enhanced Antiviral State in Dendritic Cells from HIV-1 Elite Controllers
por: Martin-Gayo, Enrique, et al.
Publicado: (2018) -
Suppression of cGAS- and RIG-I-mediated innate immune signaling by Epstein-Barr virus deubiquitinase BPLF1
por: Lui, Wai-Yin, et al.
Publicado: (2023) -
OA03-06 LB. Unique stimulatory properties of myeloid dendritic cells in individuals with "elite" HIV-1 control
por: Huang, J, et al.
Publicado: (2009)