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Cooperation between cGAS and RIG-I sensing pathways enables improved innate recognition of HIV-1 by myeloid dendritic cells in elite controllers

INTRODUCTION: Spontaneous control of HIV-1 replication in the absence of anti-retroviral therapy (ART) naturally occurs in a small proportion of HIV-1-infected individuals known as elite controllers (EC), likely as a result of improved innate and adaptive immune mechanisms. Previous studies suggest...

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Detalles Bibliográficos
Autores principales: Martin-Gayo, Enrique, Gao, Ce, Calvet-Mirabent, Marta, Ouyang, Zhengyu, Lichterfeld, Mathias, Yu, Xu G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9768436/
https://www.ncbi.nlm.nih.gov/pubmed/36569826
http://dx.doi.org/10.3389/fimmu.2022.1017164

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