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Small cell lung cancer transformation and tumor heterogeneity after sequential targeted therapy and immunotherapy in EGFR-mutant non-small cell lung cancer: A case report

BACKGROUND: Histological transformation from non-small cell lung cancer (NSCLC) to small cell lung cancer (SCLC) is one of mechanisms of the acquired resistance to epidermal growth factor receptor (EGFR)-tyrosine kinase inhibitors (TKI). However, SCLC transformation and tumor heterogeneity have neve...

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Detalles Bibliográficos
Autores principales:	Yang, Meng-Hang, Yu, Jia, Cai, Chen-Lei, Li, Wei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9768476/ https://www.ncbi.nlm.nih.gov/pubmed/36568150 http://dx.doi.org/10.3389/fonc.2022.1029282

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