Extranodal natural killer/T-cell lymphoma invading a patient’s heart: A rare case report and literature review

Extranodal NK/T-cell lymphoma (ENKTL) is a rare but aggressive subtype of non-Hodgkin lymphoma, which is derived from NK cells or T cells. There are very few cases of ENKTL invading the heart. Only 12 cases of ENKTL invading the heart have been reported in the English literature. Due to the rarity o...

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Autores principales: Xiang, Yifei, Lin, Xueqin, Cai, Xiaoling, Qu, Shuang, Lin, Kai-Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9768479/
https://www.ncbi.nlm.nih.gov/pubmed/36568165
http://dx.doi.org/10.3389/fonc.2022.1011894
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author Xiang, Yifei
Lin, Xueqin
Cai, Xiaoling
Qu, Shuang
Lin, Kai-Yang
author_facet Xiang, Yifei
Lin, Xueqin
Cai, Xiaoling
Qu, Shuang
Lin, Kai-Yang
author_sort Xiang, Yifei
collection PubMed
description Extranodal NK/T-cell lymphoma (ENKTL) is a rare but aggressive subtype of non-Hodgkin lymphoma, which is derived from NK cells or T cells. There are very few cases of ENKTL invading the heart. Only 12 cases of ENKTL invading the heart have been reported in the English literature. Due to the rarity of this lymphoma, an effective therapeutic strategy has not been defined. Here, we present a case of a 51-year-old Chinese male with extranodal NK/T-cell lymphoma invading the heart and review the literature. The patient received a chemotherapy regimen of PD1 monoclonal antibody (Sintilimab) in combination with first-line P-Gemox. The patient survived for 2 months after diagnosis.
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spelling pubmed-97684792022-12-22 Extranodal natural killer/T-cell lymphoma invading a patient’s heart: A rare case report and literature review Xiang, Yifei Lin, Xueqin Cai, Xiaoling Qu, Shuang Lin, Kai-Yang Front Oncol Oncology Extranodal NK/T-cell lymphoma (ENKTL) is a rare but aggressive subtype of non-Hodgkin lymphoma, which is derived from NK cells or T cells. There are very few cases of ENKTL invading the heart. Only 12 cases of ENKTL invading the heart have been reported in the English literature. Due to the rarity of this lymphoma, an effective therapeutic strategy has not been defined. Here, we present a case of a 51-year-old Chinese male with extranodal NK/T-cell lymphoma invading the heart and review the literature. The patient received a chemotherapy regimen of PD1 monoclonal antibody (Sintilimab) in combination with first-line P-Gemox. The patient survived for 2 months after diagnosis. Frontiers Media S.A. 2022-12-07 /pmc/articles/PMC9768479/ /pubmed/36568165 http://dx.doi.org/10.3389/fonc.2022.1011894 Text en Copyright © 2022 Xiang, Lin, Cai, Qu and Lin https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Oncology
Xiang, Yifei
Lin, Xueqin
Cai, Xiaoling
Qu, Shuang
Lin, Kai-Yang
Extranodal natural killer/T-cell lymphoma invading a patient’s heart: A rare case report and literature review
title Extranodal natural killer/T-cell lymphoma invading a patient’s heart: A rare case report and literature review
title_full Extranodal natural killer/T-cell lymphoma invading a patient’s heart: A rare case report and literature review
title_fullStr Extranodal natural killer/T-cell lymphoma invading a patient’s heart: A rare case report and literature review
title_full_unstemmed Extranodal natural killer/T-cell lymphoma invading a patient’s heart: A rare case report and literature review
title_short Extranodal natural killer/T-cell lymphoma invading a patient’s heart: A rare case report and literature review
title_sort extranodal natural killer/t-cell lymphoma invading a patient’s heart: a rare case report and literature review
topic Oncology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9768479/
https://www.ncbi.nlm.nih.gov/pubmed/36568165
http://dx.doi.org/10.3389/fonc.2022.1011894
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