Calcium regulates acid-sensing ion channel 3 activation by competing with protons in the channel pore and at an allosteric binding site

The extracellular Ca(2+) concentration changes locally under certain physiological and pathological conditions. Such variations affect the function of ion channels of the nervous system and consequently also neuronal signalling. We investigated here the mechanisms by which Ca(2+) controls the activi...

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Detalles Bibliográficos
Autores principales: Roy, Sophie, Johner, Niklaus, Trendafilov, Viktor, Gautschi, Ivan, Bignucolo, Olivier, Molton, Ophélie, Bernèche, Simon, Kellenberger, Stephan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9768671/
https://www.ncbi.nlm.nih.gov/pubmed/36541099
http://dx.doi.org/10.1098/rsob.220243

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9768671/
https://www.ncbi.nlm.nih.gov/pubmed/36541099
http://dx.doi.org/10.1098/rsob.220243

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