Phosphorylation of adducin-1 by TPX2 promotes interpolar microtubule homeostasis and precise chromosome segregation in mouse oocytes

BACKGROUND: ADD1 (adducin-1) and TPX2 (targeting protein for Xklp2) are centrosomal proteins and regulate mitotic spindle assembly. Mammalian oocytes that segregate homologous chromosomes in Meiosis I and sister chromatids in Meiosis II with a spindle lacking centrosomes are more prone to chromosome...

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Detalles Bibliográficos
Autores principales: Zhang, Ying, Fan, Bingfeng, Li, Xiaoxia, Tang, Yu, Shao, Jing, Liu, Lixiang, Ren, Yuhe, Yang, Yifeng, Xu, Baozeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9769001/
https://www.ncbi.nlm.nih.gov/pubmed/36539904
http://dx.doi.org/10.1186/s13578-022-00943-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9769001/
https://www.ncbi.nlm.nih.gov/pubmed/36539904
http://dx.doi.org/10.1186/s13578-022-00943-y

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