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Intracameral Injection of AAV-DJ.COMP-ANG1 Reduces the IOP of Mice by Reshaping the Trabecular Outflow Pathway

PURPOSE: The angiopoietin-1 (ANG1)-TIE signaling pathway orchestrates the development and maintenance of the Schlemm's canal (SC). In this study, we investigated the impact of adeno-associated virus (AAV)-mediated gene therapy with cartilage oligomeric matrix protein-ANG1 (COMP–ANG1) on trabecu...

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Detalles Bibliográficos
Autores principales:	Qiao, Yunsheng, Sun, Zhongmou, Tan, Chen, Lai, Junyi, Sun, Xinghuai, Chen, Junyi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Association for Research in Vision and Ophthalmology 2022
Materias:	Glaucoma
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9769031/ https://www.ncbi.nlm.nih.gov/pubmed/36520455 http://dx.doi.org/10.1167/iovs.63.13.15

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