Transient Polycomb activity represses developmental genes in growing oocytes

BACKGROUND: Non-genetic disease inheritance and offspring phenotype are substantially influenced by germline epigenetic programming, including genomic imprinting. Loss of Polycomb Repressive Complex 2 (PRC2) function in oocytes causes non-genetically inherited effects on offspring, including embryon...

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Detalles Bibliográficos
Autores principales: Jarred, Ellen G., Qu, Zhipeng, Tsai, Tesha, Oberin, Ruby, Petautschnig, Sigrid, Bildsoe, Heidi, Pederson, Stephen, Zhang, Qing-hua, Stringer, Jessica M., Carroll, John, Gardner, David K., Van den Buuse, Maarten, Sims, Natalie A., Gibson, William T., Adelson, David L., Western, Patrick S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9769065/
https://www.ncbi.nlm.nih.gov/pubmed/36544159
http://dx.doi.org/10.1186/s13148-022-01400-w

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