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Intranasal delivery of replicating mRNA encoding hACE2-targeting antibody against SARS-CoV-2 Omicron infection in the hamster

The Omicron variant is sweeping the world, which displays striking immune escape potential through mutations at key antigenic sites on the spike protein, making broad-spectrum SARS-CoV-2 prevention or therapeutical strategies urgently needed. Previously, we have reported a hACE2-targeting neutralizi...

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Detalles Bibliográficos
Autores principales:	Zhang, Ya-Nan, Zhang, Hong-Qing, Wang, Gui-Feng, Zhang, Zhe-Rui, Li, Jia-Qi, Chen, Xiao-Ling, Hu, Yan-Yan, Zeng, Xiang-Yue, Shi, Yu-Jia, Wang, Jing, Li, Ying-Hua, Li, Xiao-Dan, Wang, Chun-He, Zhu, Bing, Zhang, Bo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier B.V. 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9769068/ https://www.ncbi.nlm.nih.gov/pubmed/36565755 http://dx.doi.org/10.1016/j.antiviral.2022.105507

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