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Rapamycin Inhibits Light-Induced Necrosome Activation Occurring in Wild-Type, but not RPE65-Null, Mouse Retina

PURPOSE: Both photodamage and aberrant visual cycle contribute to disease progress of many retinal degenerative disorders, whereas the signaling pathways causing photoreceptor death remain unclear. Here we investigated the effects of intense photo-stress on (1) necrosome activation in wild-type and...

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Detalles Bibliográficos
Autores principales:	Lu, Chunfeng, Li, Songhua, Jin, Minghao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Association for Research in Vision and Ophthalmology 2022
Materias:	Retina
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9769341/ https://www.ncbi.nlm.nih.gov/pubmed/36534385 http://dx.doi.org/10.1167/iovs.63.13.19

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