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Antibody Recognition of CD4-Induced Open HIV-1 Env Trimers

Human immunodeficiency virus type 1 (HIV-1) envelope (Env), a heterotrimer of gp120-gp41 subunits, mediates fusion of the viral and host cell membranes after interactions with the host receptor CD4 and a coreceptor. CD4 binding induces rearrangements in Env trimer, resulting in a CD4-induced (CD4i)...

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Detalles Bibliográficos
Autores principales:	Yang, Zhi, Dam, Kim-Marie A., Gershoni, Jonathan M., Zolla-Pazner, Susan, Bjorkman, Pamela J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2022
Materias:	Structure and Assembly
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9769388/ https://www.ncbi.nlm.nih.gov/pubmed/36448805 http://dx.doi.org/10.1128/jvi.01082-22

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