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Sertraline Is an Effective SARS-CoV-2 Entry Inhibitor Targeting the Spike Protein

The global spread of the novel coronavirus severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and the continuously emerging new variants underscore an urgent need for effective therapeutics for the treatment of coronavirus disease 2019 (COVID-19). Here, we screened several FDA-approved amp...

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Detalles Bibliográficos
Autores principales: Chen, Yuliu, Wu, Yan, Chen, Shaoying, Zhan, Qingping, Wu, Dingzhou, Yang, Chan, He, Xiaoxue, Qiu, Mengjie, Zhang, Nannan, Li, Zhaofeng, Guo, Yunhua, Wen, Minjun, Lu, Lu, Ma, Cuiqing, Guo, Jiayin, Xu, Wei, Li, Xiaojuan, Li, Lin, Jiang, Shibo, Pan, Xiaoyan, Liu, Shuwen, Tan, Suiyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9769394/
https://www.ncbi.nlm.nih.gov/pubmed/36468859
http://dx.doi.org/10.1128/jvi.01245-22