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Biochemical Identification of a Nuclear Coactivator Protein Required for AtrR-Dependent Gene Regulation in Aspergillus fumigatus

Azole drugs represent the primary means of treating infections associated with the filamentous fungal pathogen Aspergillus fumigatus. A central player in azole resistance is the Zn(2)Cys(6) zinc cluster-containing transcription factor AtrR. This factor stimulates expression of both the cyp51A gene,...

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Detalles Bibliográficos
Autores principales: Paul, Sanjoy, Ror, Shivani, McDonald, W. Hayes, Moye-Rowley, W. Scott
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9769526/
https://www.ncbi.nlm.nih.gov/pubmed/36374043
http://dx.doi.org/10.1128/msphere.00476-22