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Biochemical Identification of a Nuclear Coactivator Protein Required for AtrR-Dependent Gene Regulation in Aspergillus fumigatus
Azole drugs represent the primary means of treating infections associated with the filamentous fungal pathogen Aspergillus fumigatus. A central player in azole resistance is the Zn(2)Cys(6) zinc cluster-containing transcription factor AtrR. This factor stimulates expression of both the cyp51A gene,...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Society for Microbiology
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9769526/ https://www.ncbi.nlm.nih.gov/pubmed/36374043 http://dx.doi.org/10.1128/msphere.00476-22 |