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Rapid Point-of-Care Tests Using Staphylococcal Protein A Can Detect Early IgM Responses in HIV-1 and Treponema pallidum Infections

Serological assays detecting IgM antibodies in addition to IgG antibodies have a diagnostic advantage in finding early infections. Staphylococcal protein A (SpA), widely used as an antibody-detecting reagent in various immunoassays, is considered to have a high binding affinity mainly to IgG, althou...

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Detalles Bibliográficos
Autores principales: Schmidt, Valentina A., Stevens, Victoria Rose, Esfandiari, Javan, Lyashchenko, Konstantin P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9769532/
https://www.ncbi.nlm.nih.gov/pubmed/36453925
http://dx.doi.org/10.1128/spectrum.03309-22