Chemotherapeutic Drugs Induce Different Gut Microbiota Disorder Pattern and NOD/RIP2/NF-κB Signaling Pathway Activation That Lead to Different Degrees of Intestinal Injury

5-Fluorouracil (5-FU), irinotecan (CPT-11), oxaliplatin (L-OHP), and calcium folinate (CF) are widely used chemotherapeutic drugs to treat colorectal cancer. However, chemotherapeutic use is often accompanied by intestinal inflammation and gut microbiota disorder. Changes in gut microbiota may destr...

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Detalles Bibliográficos
Autores principales: Huang, Bin, Gui, Mengxuan, Ni, Zhuona, He, Yanbin, Zhao, Jinyan, Peng, Jun, Lin, Jiumao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9769542/
https://www.ncbi.nlm.nih.gov/pubmed/36222691
http://dx.doi.org/10.1128/spectrum.01677-22

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9769542/
https://www.ncbi.nlm.nih.gov/pubmed/36222691
http://dx.doi.org/10.1128/spectrum.01677-22

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